Mid-term outcomes of minimally invasive surgery for partial atrioventricular septal defect in children

Anh Tien Do1,2, Tran Thuy Nguyen1,2,
1 University of Medicine and Pharmacy – Vietnam National University, Hanoi
2 E Hospital

Main Article Content

Abstract

Objective: This study aims to describe the mid-term outcomes of minimally invasive surgery for partial atrioventricular septal defect in children.


Summary: Partial atrioventricular septal defect is one of the three types of atrioventricular septal defect, accounting for about 3.5% of congenital heart disease. Traditionally, complete repair has been performed via sternotomy. However, with the advancement of minimally invasive surgical techniques in treating congenital heart conditions, we conducted this study to assess the feasibility and mid-term outcomes of this approach.


Subjects and methods: This descriptive study spanned from January 2018 to December 2023, involving 30 patients diagnosed with partial atrioventricular septal defect who underwent minimally invasive complete repair. The cohort comprised 12 males and 18 females, with an average age of 18 months and average weight of 10.3 kg. The mean diameter of the primary atrial septal defect was 15 mm. Eight patients (26.7%) exhibited moderate to severe mitral regurgitation, and the average pulmonary artery pressure was 37 mmHg.


Results: The average durations of cardiopulmonary bypass and aortic cross-clamp were  82 minutes and 58 minutes, respectively. None of the patients required sternotomy. The average time of artificial ventilator post-surgery was 6.9 hours, with a mean hospital stay of 7.6 days. Postoperative echocardiography showed promising results: complete closure of atrial septal defect, with 90% of patients having absent or mild mitral valve regurgitation, only 10% experienced moderate mitral valve regurgitation. The average follow-up period was 38 months, during which there were no postoperative fatalities. One patient required reoperation due to severe mitral regurgitation from an anterior cleft.


Conclusion: Minimally invasive surgery for partial atrioventricular septal defect in children can be safely performed, yielding favorable mid-term outcomes during follow-up.

Article Details

References

1. Devlin, P.J., et al., Repair of Partial Atrioventricular Septal Defect: Age and Outcomes. Ann Thorac Surg, 2016. 102(1): p. 170-7.
2. Nakayama, Y., et al., Surgical Outcomes in Children With Partial and Transitional Atrioventricular Septal Defect. World J Pediatr Congenit Heart Surg, 2022. 13(4): p. 451-457.
3. Zhu, J., et al., Individualized strategy of minimally invasive cardiac surgery in congenital cardiac septal defects. J Cardiothorac Surg, 2022. 17(1): p. 5.
4. Chowdhury, U.K., et al., Specific issues after surgical repair of partial atrioventricular septal defect: actuarial survival, freedom from reoperation, fate of the left atrioventricular valve, prevalence of left ventricular outflow tract obstruction, and other events. J Thorac Cardiovasc Surg, 2009. 137(3): p. 548-555 e2.
5. Dodge-Khatami, J., et al., Mini right axillary thoracotomy for congenital heart defect repair can become a safe surgical routine. Cardiol Young, 2022: p. 1-4.
6. Horer, J., Right Axillary Thoracotomy in Congenital Cardiac Surgery: Why, for Whom, and How? Ann Thorac Surg, 2021. 112(6): p. 2053-2054.
7. Dodge-Khatami, J. and A. Dodge-Khatami, Advantages of a mini right axillary thoracotomy for congenital heart defect repair in children. Cardiol Young, 2022. 32(2): p. 276-281.
8. Luo, Z.R., et al., Comparative Study between Surgical Repair of Atrial Septal Defect via Median Sternotomy, Right Submammary Thoracotomy, and Right Vertical Infra-Axillary Thoracotomy. Braz J Cardiovasc Surg, 2020. 35(3): p. 285-290.
9. Istar, H. and U. Sevuk, Minimally invasive cardiac surgery in low-resource settings: right vertical infra-axillary mini-thoracotomy without peripheral cannulation - the first 100 cases. Eur Rev Med Pharmacol Sci, 2023. 27(13): p. 6247-6255.
10. Myers, P., T. Sologashvili, and R. Pretre, Non-visible scar surgery: Right axillary thoracotomy approach for partial atrioventricular canal repair. Multimed Man Cardiothorac Surg, 2019. 2019.