Early result of minimally invasive cardiac myxoma resection at University Medical Center, Ho Chi Minh City

Thi Thuy Ngoc Le, Hoang Dinh Nguyen1,
1 University of Medicine and Pharmacy at Ho Chi Minh City

Main Article Content

Abstract

Objective: The study aimed to evaluate various clinical and paraclinical characteristics, as well as early surgical outcomes of minimally invasive cardiac myxoma resection at University Medical Center HCMC.


Subjects and methods: This is a retrospective descriptive case series study involving all patients diagnosed with cardiac myxomas who underwent minimally invasive surgery at University Medical Center HCMC from January 2020 to June 2024.


Results: There were 31 patients, consisting of 22 females and 9 males. The mean age was 56,2 ± 10,7 years old (from 37 to 77 years old). The clinical manifestations were diverse: asymptomatic (45,2%), cerebral embolism (6,4%), fatigue (29,0%), dyspnea (35,5%), palpitations (12,9%), and dizziness (12,9%). Echocardiographic results: 90,3% left atrial myxoma, 9,7% right atrial myxoma. The tumor attachment sites: interatrial septum (93,6%), left atrial wall (6,4%). The average tumor size was 36,3 ± 15,1 mm. All tumors were completely resected (100%). Additional surgical procedures: mitral valve repair (3,2%), interatrial septum repair (6,4%). Cardiopulmonary bypass time was 82,4 ± 31,1 minutes (from 49 to 199 minutes), cross - clamp time was 39,2 ± 17,6 minutes (from 18 to 85 minutes), with 3 cases not requiring cardiac arrest. Ventilation time was 13,2 ± 6,3 hours (from 6,7 to 32,4 hours), intensive care unit stay was 52,6 ± 28,1 hours (from 13 to 113,7 hours), postoperative recovery time was 6,9 ± 2,3 days (from 4 to 16 days). Early outcomes: 3 cases of atrial fibrillation with rapid ventricular response, treated medically (9,7%), 1 case of acute kidney injury (3,2%), 4 cases of pleural effusion (12,9%), 3 cases of pneumothorax (9,7%), 1 case of right external iliac artery thrombosis requiring surgical thrombectomy (3,2%), and 2 cases of deep vein thrombosis (6,4%). No surgical site infections, cerebrovascular accidents, or mortality within 30 days post-surgery were reported.


Conclusion: Minimally invasive cardiac myxoma resection demonstrates a low complication rate, with no reported tumor recurrence or early postoperative mortality. This technique offers a safe and effective alternative to traditional median sternotomy and may be gradually adopted and implemented in lower - level healthcare facilities.

Article Details

References

1. Reynen K. Cardiac myxomas. The New England journal of medicine. Dec 14 1995;333(24):1610-7. doi:10.1056/nejm199512143332407
2. Basso C, Valente M, Thiene G. Cardiac tumor pathology. Springer science and business media New York 2013; 2013.
3. Daniel J. Goldstein MCO. Minimally invasive cardiac surgery. 2004.
4. Muhammad Habib Zubair JMS. Updates in Minimally Invasive Cardiac Surgery for General Surgeons. Surgical Clinics of North America. 2017;Volume 97(4)doi:https://doi.org/10.1016/j.suc.2017.03.002.
5. Lawrence H.Cohn M. Cardiac surgery in the adult. third ed. 2008:1479-1490.
6. Karel M Van Praet M, Markus Kofler M, MSc, Wilkens K, et al. Minimally invasive extirpation of benign atrial cardiac tumors: clinical follow-up and survival. Innovations technology and techniques in cardiothoracic and vascular surgery. 2023;18(3):232-239. doi:DOI: 10.1177/15569845231170000
7. Giacomo Bianchi M, PhD, Rafik Margaryan M, PhD, Enkel Kallushi M, et al. Outcomes of video-assisted minimally invasive cardiac myxoma resection. Heart, Lung and Circulation 2019;28(2):327-333.
8. Hùng LT, Đạt PT, Nam NH, et al. Kết quả sớm phẫu thuật ít xâm lấn cắt u nhầy nhĩ trái tại Trung tâm Tim mạch Bệnh viện E. Tạp chí Phẫu thuật Tim mạch và Lồng ngực Việt Nam. 2022:5-12.
9. Nektaria M, Theologou S, Christos C, et al. Cardiac myxomas: A single-center case series of 145 patients over a 32-year period study. Annals of cardiac anaesthesia. Jan-Mar 2023;26(1):17-22. doi:10.4103/aca.aca_290_20
10. Changwon Shin M, Min Ho Ju M, Chee-Hoon Lee M, Mi Hee Lim M, Ph.D, Hyung Gon Je M, Ph.D. Surgical outcomes of cardiac myxoma resection through right mini-thoracotomy. Journal of Chest Surgery. 2023;56(1):42-48.
11. Liêm ĐN, Hiền NS, Huy ĐQ, Ngọc NM, Tú VN. Kết quả sớm phẫu thuật nội soi điều trị u nhày nhĩ trái tại Bệnh viện tim Hà Nội giai đoạn 2018–2021. Tạp chí Y học Việt Nam. 2022;518(1):11-15.
12. Shah IK, Dearani JA, Daly RC, et al. Cardiac Myxomas: A 50-Year Experience With Resection and Analysis of Risk Factors for Recurrence. Ann Thorac Surg. Aug 2015;100(2):495-500. doi:10.1016/j.athoracsur.2015.03.007