STUDY ON THE RELATION BETWEEN POST-OPERATIVE SERUM GLUCOSE LEVELS AND SEVERITY IN PATIENTS UNDERGOING OPEN HEART SURGERY

Le Minh Khoi, Nguyen Hoang Dinh

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Abstract

Introduction: Hyperglycemia is frequently encounted in patients undergoing cardiac surgery with cardiopulmonary bypass support. Post-operative hyperglycemia is associated with an increased mortality and morbidity in these patients.


Objectives: To investigate the relationship between post-operative blood glucose levels and severity in patients undergoing open heart surgery.


Patients and Methods: All patients undergoing cardiac surgery with cardiopulmonary bypass were recruited. Blood glucose levels were determined before, right after surgery and at 6am every day until discharge from the intensive care unit.


 Results: Patients who had blood glucose above 140mg/dL right after surgery or in the first post-op day had significantly longer duration of ventilation and intensive care unit stay al well as increased number of vasoactive drugs used.
Conclusions: Hyperglycemia was associated with increased severity in patients undergoing cardiac surgery with cardiopulmonary bypass support.

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References

1. Treggiari MM, Karir V, Yanez ND et al (2008). Intensive insulin therapy and mortality in critically
ill patients. Critical Care, 12:R29 (doi:10.1186/cc6807)
2. Chinsky K (2004). The evolving paradigm of hyperglycemia and critical illness. Chest, 126:
674-676
3. Capes S, Hunt D, Malmberg K et al (2000). Stress hyperglycemia and increased risk of death after myocardial infarction in patients with and without diabetes: a systematic overview. Lancet,
355: 773-778.
4. Gandhi GY, Nuttall GA, Abel MD et al (2005). Intraoperative Hyperglycemia and Perioperative Outcomes in Cardiac Surgery Patients. Mayo Clin Proc, 80(7):862-866.
5. Finfer S, Delaney A (2008). Tight Glycemic Control in Critically Ill Adults. JAMA, 300: 963-965.
6. Lê Minh Khôi (2012). Nghiên cứu hiệu quả và tính an toàn của insulin tĩnh mạch trong điều trị tăng đường huyết sau phẫu thuật tim. Y học Thành phố Hồ Chí Minh, Phụ bản của tập 16, số 1: 337-342.
7. Nguyễn Thị Băng Sương, Nguyễn Hoàng Định, Lê Minh Khôi (2012). Nghiên cứu tình trạng tăng glucose máu trong giai đoạn hậu phẫu ở bệnh nhân mổ tim hở có hỗ trợ tuần hoàn ngoài cơ thể. Y học Thành phố Hồ Chí Minh, Phụ bản của tập 16, số 1: 206-211.
8. Furnary AP, Wu Y (2006). Clinical effects of hyperglycemia in the cardiac surgery population: the Portland Diabetic Project. Endocr Pract, 3: 22-26.
9. Ghafoori AF, Twite MD, Friesen RH (2008). Postoperative hyperglycemia is associated with mediastinitis following pediatric cardiac surgery. Paediatr Anaesth, 18: 1202-1207.