Comparison of analgesic efficacy between erector spine plane block and intravenous patient-controlled analgesia with morphin after open heart surgery

Vu Thi Thuc Phuong , Bui Duc Tam, Tran Cong Thanh

Main Article Content

Abstract

Pain after cardiac surgery is always an obsession of patients and a top concern of anesthesiologists. Experimental subjects challenged by acute pain and patients in chronic pain experience impairments in attention control, working memory, mental flexibility, problem solving, and information processing speed. The two most commonly used analgesia methods are patient-controlled analgesia (PCA) and erector spinea plane block (ESP). Our study aimed to compare the analgesic effect of ESP with PCA in patients after cardiac surgery using extracorporeal circulation and evaluate the disavantages of these two pain relief techniques. Subject and methods: This study was a randomized controlled intervention study of adult patients who underwent open-heart surgery patients with extracorporeal circulation from May 2020 to September 2021 in the Department of Anesthesiology and Intensive Care Unit - Hanoi Heart Hospital. Results: Two hundred and four (204) consecutive patients were collected, included 108 patients in the ESP group and 96 patients in the PCA group. The mean intraoperative fentanyl amount in the ESP group (0.57±0.50 mg) was lower than in the PCA group (1.00±0.00 mg) (p<0.05). The average VAS score when the patient was lying still and taking deep breaths at the time of assessment in both groups was below 3 (corresponding to low pain level) (p>0.05). The mean morphin consumption 24 hours after surgery was significantly lower in the ESP group (0,23±0,12 mg) than in the PCA group (17,92±3,32 mg) (p<0.05). The mean time after surgery in the ESP group (3.80±1.02 hours) and the PCA group (5.21±1.10 hours) had a clear difference between p<0.05. The mean time of extubation in the ESP group (8.06±1.60 hours) was statistically significantly lower than in the PCA group (8.83±1.43 hours) (p<0.05). The rate of nausea in the ESP group (20.98%) was lower than in the PCA group (58.33%) (p<0.05). Conclusion: Both methods had good analgesic effect with an average VAS score ≤ 3. The ESP group had a lower mean postoperative morphine consumption, a higher patient satisfaction level, and a lower rate of nausea, vomiting, and slow breathing statistically significant less than the PCA group.

Article Details

References

1. Nachiyunde, B., & Lam, L. “The efficacy of different modes of analgesia in postoperative pain management and early mobilization in postoperative cardiac surgical patients: A systematic review.” Annals of cardiac anaesthesia vol. 21,4 (2018): 363-370.
2. Zubrzycki, M., Liebold, A., Skrabal, C., Reinelt, H., Ziegler, M., Perdas, E., & Zubrzycka, M. "Assessment and pathophysiology of pain in cardiac surgery." Journal of pain research 11 (2018): 1599.
3. Imantalab, V., Mirmansouri, A., Jouryabi, A. M., et al. "Comparing the effectiveness of patient control analgesia pump and bolus morphine in controlling pain after cardiopulmonary bypass graft surgery." Anesthesiology and pain medicine 7.5 (2017).
4. Forero, M., Adhikary, S. D., Lopez, H., Tsui, C., & Chin, K. J. "The erector spinae plane block: a novel analgesic technique in thoracic neuropathic pain." Regional Anesthesia & Pain Medicine 41.5 (2016): 621-627.
5. Macaire, P., Ho, N., Nguyen, T., Nguyen, B., Vu, V., Quach, C., Roques, V. and Capdevila, X. "Ultrasound-guided continuous thoracic erector spinae plane block within an enhanced recovery program is associated with decreased opioid consumption and improved patient postoperative rehabilitation after open cardiac surgery-a patient-matched, controlled before-and-after study." Journal of cardiothoracic and vascular anesthesia 33.6 (2019): 1659-1667.
6. Chin, K. J., Adhikary, S. D., & Forero, M. "Erector spinae plane (ESP) block: A new paradigm in regional anesthesia and analgesia." Current Anesthesiology Reports 9.3 (2019): 271-280.
7. Vaughan, B. N., Bartone, C. L., McCarthy, C. M., Answini, G. A., & Hurford, W. E. "Ultrasound-Guided Continuous Bilateral Erector Spinae Plane Blocks Are Associated with Reduced Opioid Consumption and Length of Stay for Open Cardiac Surgery: A Retrospective Cohort Study." Journal of Clinical Medicine 10.21 (2021): 5022.
8. Đức, T. V., Phương, V. H., Oanh, Đ. T. T., Quỳnh, N. T., Chung, N. V., Hương, H. T., & Tú, N. H. "Hiệu quả giảm đau sau mổ của phương pháp gây tê mặt phẳng cơ dựng sống (erector spinae plane block) cho phẫu thuật tim hở." Tạp chí Nghiên cứu Y học 147.11 (2021): 219-227.
9. Sobhy, M. G., Abd El-Hamid, A. M., Elbarbary, D. H., & Elmeliegy, M. F. "Ultrasound-guided erector spinae block for postoperative analgesia in thoracotomy patients: a prospective, randomized, observer-blind, controlled clinical trial." Ain-Shams Journal of Anesthesiology 12.1 (2020): 1-7.
10. Adhikary, S. D., Bernard, S., Lopez, H., & Chin, K. J. "Erector spinae plane block versus retrolaminar block: a magnetic resonance imaging and anatomical study." Regional Anesthesia & Pain Medicine 43.7 (2018): 756-762.