Early result of minimally invasive left atrial myxoma resection at Cardiovascular Center - E hospital

Le The Hung, Pham Thanh Dat, Nguyen Hoang Nam, Do Duc Thinh, Nguyen Tran Thuy, Le Ngoc Thanh, Nguyen Cong Huu

Main Article Content

Abstract

Objectives: The study aimed to evaluate clinical and paraclinical characteristics of left atrial myxoma and the early result of minimally invasive left atrial myxoma resection at E hospital.


Patients and methods: This is retrospective, descriptive study of consecutive patients, who underwent minimally invasive left atrial myxoma rejection, using total or video-assisted endoscopic technique from October 2016 to March 2021 at E hospital. There were 31 patients, consisting of 27 females and 04 males. The mean age was 53 ± 13 years old (range [17-74]).


Results: Preoperative clinical manifestations were diverse. Asymptomatic form was in 3 patients (9.7%), hemodynamic symptoms were in 26 patients (83.9%), embolism were presented in 4 patients (12.9%), systemic symptoms were in 8 patients (25.8%). Anemia and elevated erythrocyte sedimentation rates were observed in 45.2% and 74.2%, respectively. Echocardiography results: the average tumor size was 4.2 ± 1.7 cm (range [1.7-8]), the site of attachment was mainly in the atrial septum (77.4%). Cardiopulmonary bypass time was 158 ± 43 minutes (range [100-252]), cross-clamp time was 84 ± 34.2 minutes (range [42-153]), ventilation time was 10,8 ± 7,0 hours (range [3-30]), intensive care unit stay was 1,5 ± 1,0 days (range [0.5-4]), and in-hospital stay was 9.5 ± 5.0 days (range [3-30]). There was no hospital mortality. Cerebrovascular accident was presented in one (3.2%), femoral artery stenosis was in one (3.2%), atrial fibrillation after surgery was in one(3.2%).There was no bleeding, that require reoperation, and no other serious complications.


Conclusions: Initial results of left atrial myxoma resection, using minimally invasive total or video-assisted technique wassafe and effectivewith low complications, could be recommended toapply routinely in cardiac surgery centers.

Article Details

References

1. Basso C, Valente M, Thiene G (2013). Cardiac Tumor Pathology, Humana Press ,Totowa, NJ.
2. Ipek G et al (2005). Surgical Management of Cardiac Myxoma. J Card Surg, 20(3), 300–304.
3. Hoffmeier A, Sindermann J R, Scheld H H et al (2014). Cardiac tumors--diagnosis and surgical treatment. Dtsch Arztebl Int, 111 (12), 205-211
4. Karabinis A, Samanidis G, Khoury M, Stavridis G, Perreas K (2018). Clinical presentation and treatment of cardiac myxoma in 153 patients. Medicine (Baltimore), 97(37), e12397.
5. Pinede L, Duhaut P, Loire R. (2001 ) Clinical presentation of left atrial cardiac myxoma A series of 112 consecutive cases .Medicine ( Baltimore ), 80(3), 159-172
6. Bulkley B H, Hutchins G M (1979). Atrial myxomas: A fifty year review. Am Heart J, 97(5), 639–643.
7. Nasser W K et al(1972). Atrial myxoma, Am. Heart J, 83(5), 694-704
8. Richardson J V, Brandt B et al (1979). Surgical Treatment of Atrial Myxomas: Early and Late Results of 11 Operations and Review of the Literature. Ann Thorac Surg, 28(4), 354–358.
9. Peters M N, Hall R J, Leachman R D, Garcia E. The Clinical Syndrome of Atrial Myxoma. JAMA, 230(5), 695-701.
10. Blondeau et al (1990). Primary Cardiac Tumors - French Studies of 533 Cases. Thorac Cardiovasc Surg, 38(S 2), 192–195.
11. Markel M L et al (1987). Cardiac myxoma A review. Medicine, 66(2), 114-125.
12. Pinede L, Duhaut P, Loire R (2001). Clinical Presentation of Left Atrial Cardiac Myxoma: A Series Of 112 Consecutive Cases. Medicine (Baltimore), 80(3), 159–172.
13. Knepper L E, Biller J, Adams H P, Bruno A (1988). Neurologic manifestations of atrial myxoma. A 12-year experience and review. Stroke, 19(11), 1435–1440.
14. Giuliani ER et al (1980). CNS Embolism due to Atrial Myxoma Clinical Features and Diagnosis. Arch neuron, 37, 485-487
15. Reynen K et al (1995). Cardiac myxoma. The New England Journal Of Medicine, 333(24),1610-1617.
16. Yüksel A, Saba D, Velioğlu Y, Ener S, Özkan H (2016). Biatrial Approach Provides Better Outcomes in the Surgical Treatment of Cardiac Myxomas. Braz J Cardiovasc Surg, 31(4),309-317.
17. Yu S H, Lim S H, Hong Y S,et al (2006). Clinical Experiences of Cardiac Myxoma. Yonsei Medical Journal, 47(3), 367-371.
18. Despande R P et al (2007). Endoscopic cardiac tumor resection, Ann Thorac Surg 83, 2142-2146
19. Vistarini N et al (2010). Minimally invasive video assisted approach for left atrial myxoma resection, Interactive cardiovascular and thoracic surgery, 9-11
20. Shiqiang Yu et al (2010). Totally thoracoscopic surgical resection of cardiac myxoma in 12 patients, Ann Thorac surg 90, 674-676
21. Gao C, Yang M, Wang G, Wang J (2008). Totally robotic resection of myxoma and atrial septal defect repair. Interact Cardiovasc Thorac Surg.;7(6), 947-950