Outcomes of endovascular treatment for acute aortic syndrome at Thong Nhat Hospital

Nguyen Duy Tan1,2, Huynh Ngoc Hanh1, Lam Thao Cuong3,4,
1 Thong Nhat Hospital
2 School of Health Sciences, Vietnam National University Ho Chi Minh City
3 University Medical Center Ho Chi Minh City
4 University of Medicine and Pharmacy Ho Chi Minh City

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Tóm tắt

Introduction: Acute aortic syndrome (AAS) is a life-threatening emergency encompassing aortic dissection, intramural hematoma (IMH), penetrating aortic ulcer (PAU), and aortic rupture/pseudoaneurysm. Mortality reaches 50–90% without timely intervention. Endovascular stent-grafting has become the preferred approach for descending aortic lesions.


Objective: To evaluate clinical characteristics, lesion morphology, and early outcomes of endovascular treatment for AAS at Thong Nhat Hospital.


Methods: A retrospective descriptive study of 22 patients diagnosed with AAS and treated by endovascular stent-grafting from June 2020 to January 2024. Lesion classification followed the Svensson system and the 2014 ESC Guidelines. Categorical variables were analyzed using Fisher’s exact test; continuous variables using the independent samples t-test.


Results: 22 patients (male 72.7%; mean age 58.5 ± 14.2 years). Lesion types: aortic dissection 45.5%, aortic rupture/pseudoaneurysm 27.3%, PAU 22.7%, IMH 4.5%. Most common proximal landing zones: zone 0 (22.7%) and zone 2 (36.4%). Supra-aortic vessel transposition was required in 68.2% of cases. Technical success rate was 77.3%. Complications (each 4.5%): endoleak, retrograde type A dissection, aortic/iliac rupture, cerebral embolism, and acute limb ischemia. In-hospital mortality was 9.1% (2/22).


Conclusion: Endovascular stent-grafting is a feasible, safe and effective treatment for AAS with acceptable in-hospital mortality. Larger cohorts and longer follow-up are needed to evaluate mid- and long-term outcomes.

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Tài liệu tham khảo

1. Erbel R, Aboyans V, Boileau C, et al; ESC Committee for Practice Guidelines. 2014 ESC Guidelines on the diagnosis and treatment of aortic diseases. Eur Heart J. 2014;35(41):2873-2926. doi:10.1093/eurheartj/ehu281
2. Hagan PG, Nienaber CA, Isselbacher EM, et al. The International Registry of Acute Aortic Dissection (IRAD): new insights into an old disease. JAMA. 2000;283(7):897-903. doi:10.1001/jama.283.7.897
3. Trimarchi S, Nienaber CA, Rampoldi V, et al. Contemporary results of surgery in acute type A aortic dissection: the International Registry of Acute Aortic Dissection experience. J Thorac Cardiovasc Surg. 2005;129(1):112-122. doi:10.1016/j.jtcvs.2004.09.005
4. Nong Huu Tho. Morphological characteristics and surgical outcomes of acute thoracic aortic syndrome [Doctoral thesis]. University of Medicine and Pharmacy Ho Chi Minh City; 2022. [In Vietnamese]
5. Nienaber CA, Rousseau H, Eggebrecht H, et al. Randomized comparison of strategies for type B aortic dissection: the INvestigation of STEnt Grafts in Aortic Dissection (INSTEAD) trial. Circulation. 2009;120(25):2519-2528. doi:10.1161/CIRCULATIONAHA.109.886408
6. Nienaber CA, Clough RE. Management of acute aortic dissection. Lancet. 2015;385(9970):800-811. doi:10.1016/S0140-6736(14)61005-9
7. Isselbacher EM, Preventza O, Black JH 3rd, et al. 2022 ACC/AHA Guideline for the Diagnosis and Management of Aortic Disease: A Report of the American Heart Association/American College of Cardiology Joint Committee on Clinical Practice Guidelines. J Am Coll Cardiol. 2022;80(24):e223-e393. doi:10.1016/j.jacc.2022.08.004
8. Shu C, He H, Li QM, et al. Endovascular repair of complicated acute type-B aortic dissection with stent-graft: early and mid-term results. Eur J Vasc Endovasc Surg. 2011;42(4):448-453. doi:10.1016/j.ejvs.2011.05.013
9. Evangelista A, Isselbacher EM, Bossone E, et al; IRAD Investigators. Insights from the International Registry of Acute Aortic Dissection: a 20-year experience of collaborative clinical research. Circulation. 2018;137(17):1846-1860. doi:10.1161/CIRCULATIONAHA.117.031264
10. Dong ZH, Fu WG, Wang YQ, et al. Retrograde type A aortic dissection after endovascular stent graft placement for treatment of type B dissection. Circulation. 2009;119(5):735-741. doi:10.1161/CIRCULATIONAHA.108.800540