Giant immature teratoma resection at Dong Nai General Hospital: A case report

Tuan Anh Vo1,, Thoi Hai Nguyen Nguyen2
1 Bệnh viện Đa khoa Đồng Nai
2 Dong Nai General Hospital

Main Article Content

Abstract

Introduction: Mediastinal teratoma is a disease that develops silently and can reach large sizes asymtomatically. Computed tomography is a gold standard for diagnosis and treatment strategy. We report a case of radical surgical resection of an immature mediastinal teratoma.


Case report: A 18 year-old male patient admitted to the hospital due to shrotness of breath. Contrast-enhanced computed tomography showed a mediastinal tumor of 132 x 135 x 200 mm. The tumor occupied nearly the entire left pleural space, compressed the heart and its large blood vessels to the right. The tumor was entirely resected via the median sternotomy. The pathology result was immature teratoma. Postoperative course was favorable, the patient was discharged from the hospital on postoperative day 7.


Conclusion: Immature teratoma is a malignant disease with poor long-term prognosis. Surgery is a proven effective treatment. Initial successful results at a provincial hospital contribute to helping the surgical team develop techniques and continue to perform complex surgeries, the patients need not to travel long distances and thus decrease the treatment cost.

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References

1. Goyal VD, Pahade A, Misra G, Kaira V, Prajapati N. Large mediastinal/thoracic benign teratoma presenting with haemoptysis: Report of a case and review of the literature. Lung India. Mar-Apr 2023;40(2):155-160. doi:10.4103/lungindia.lungindia_198_22
2. Kang J, Mashaal H, Anjum F. Mediastinal Germ Cell Tumors. StatPearls. 2024.
3. Mardani P, Naseri R, Amirian A, et al. Intrapulmonary mature cystic teratoma of the lung: case report of a rare entity. BMC Surg. Sep 14 2020;20(1):203. doi:10.1186/s12893-020-00864-y
4. Wang R, Li H, Jiang J, Xu GJTCR. Incidence, treatment, and survival analysis in mediastinal malignant teratoma population. 2020. 2020;9(4):2492-2502.
5. Cung Văn Công. U quái thành thục lành tính trong trung thất ở bệnh nhi - báo cáo ca bệnh và xem xét tài liệu liên quan. Tạp chí Y học Việt Nam. 2022;522:53-60.
6. Mustafa OM, Mohammed SF, Aljubran A, Saleh WN. Immature mediastinal teratoma with unusual histopathology: A case report of multi-lineage, somatic-type malignant transformation and a review of the literature. Medicine (Baltimore). Jun 2016;95(26):e3378. doi:10.1097/MD.0000000000003378
7. No TH, Seol SH, Seo GW, et al. Benign Mature Teratoma in Anterior Mediastinum. J Clin Med Res. Sep 2015;7(9):726-8. doi:10.14740/jocmr2270w
8. Moraru L, Mitranovici MI, Chiorean DM, et al. Immature Teratoma: Diagnosis and Management-A Review of the Literature. Diagnostics (Basel). Apr 23 2023;13(9)doi:10.3390/diagnostics13091516
9. Tian Z, Liu H, Li S, et al. Surgical treatment of benign mediastinal teratoma: summary of experience of 108 cases. J Cardiothorac Surg. Feb 17 2020;15(1):36. doi:10.1186/s13019-020-1075-8.