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Date Published: 24/10/2025
Abstract Views: 24
Views PDF: 7
DOI: 10.47972/vjcts.v53i.1539
Issue
Vol. 53
Section
Research Article
How to Cite
Nguyen, V. T., Dao, T. T. N., Dang, T. H., Nguyen, T. T., Tran, V. D., Lo, T. T. T., Nguyen, T. H., & Phi, T. N. (2025). Evaluating changes in some hematological and blood biochemical parameters of pediatric patients before and after complete repair surgery for tetralogy of Fallot in Cadiovascular center – E Hospital. The Vietnam Journal of Cardiovascular and Thoracic Surgery, 53, 15 - 22. https://doi.org/10.47972/vjcts.v53i.1539

Evaluating changes in some hematological and blood biochemical parameters of pediatric patients before and after complete repair surgery for tetralogy of Fallot in Cadiovascular center – E Hospital

Van Thanh Nguyen, Thi Thanh Nga Dao, Thi Huyen Dang, Thi Thuy Nguyen, Van Dai Tran, Thi Tu Trinh Lo, Thi Huong Nguyen, Thi Nguyet Phi1,
1 E Hospital

Main Article Content

Abstract

Introduction: Tetralogy of Fallot (TOF) is a common cyanotic congenital heart disease (CHD). Currently, total correction surgery using cardiopulmonary bypass (CPB) is considered the optimal method of treatment. However, CPB also has adverse effects, causing damage to organs such as the kidneys, brain, and heart. Based on these observations, we conducted this study to evaluate changes in certain hematological and biochemical indices in pediatric patients before and after total correction of Tetralogy of Fallot. Subjects and Methods: A descriptive, retrospective study was conducted on 175 patients who met the inclusion criteria. All patients were under 16 years old, diagnosed with Tetralogy of Fallot, and underwent total correction surgery. Results: The percentages of patients with decreased RBC, HGB, and HCT post-surgery were 82.9%, 69.7%, and 76.0%, respectively. The percentages of patients with increased Urea, Creatinine, GOT, and GPT post-surgery were 73.1%, 57.1%, 70.3%, and 64.0%, respectively. Conclusion: Patients showed positive changes in hematological indices after surgery, though liver and kidney effects were common.

Keywords

Fallot 4, extracorporeal circulation

Article Details

References

[1] Philippe, "Tetralogy of Fallot," In Cardiologie ELLIPSES/ AUPELF, pp. 416-420, 1994.
[2] Bao L.T, Results of surgery to completely repair Tetralogy of Fallot at the National Children's Hospital, Hanoi Medical University: Master's thesis, 2021.
[3] Minh N.A, Research on clinical and paraclinical characteristics and results of radical surgery for tetralogy of Fallot in children at the National Children's Hospital, Hanoi Medical University. General practitioner graduation thesis, 2012.
[4] Hung T. M, Research on changes in concentration andprognostic value of low cardiac output, early results after correction of total tetralogy of Fallot in pediatric patients of ultrasensitive Troponin T, Hanoi Medical University: Doctoral thesis, 2018.
[5] Thuu L.Q,Research on surgical treatment for total repair of tetralogy of Fallot, Military Medical Academy: Doctoral thesis in Medicine, 2008.
[6] S. S. K. S. e. a. Kim H, "Early and late outcomes of total repair of tetralogy of Fallot: risk factors for late right ventricular dilatation," Interact Cardiovasc Thorac Surg. 17(6), 2013, pp. 956-962.
[7] Du N. K, "Surgery for heart diseases", Medical Publishing House, 1983, pp. 1-3.
[8] Khang N. P, "Clinical Cardiology," Medical Publishing House, 2007, pp. 395-399.
[9] Hien N. S, Research on application of right ventricular non-opening technique in radical surgical treatment of tetralogy of Fallot at Hanoi Heart Hospital, Hanoi Medical University: Doctoral thesis in Medicine, 2011.
[10] Viet P. H, Evaluation of early changes in shape and hemodynamics of the heart after radical surgery for tetralogy of Fallot using Dopple ultrasound, Hanoi Medical University: Doctor of Medicine thesis, 2006.
[11] Kinh N. Q, Research on kidney dysfunction in patients with open heart surgery under extracorporeal circulation, Hanoi Medical University: Doctoral thesis in medicine, 2002.
[12] B. J. A. W. e. a. Abel RM, "Etiology, incidence, and prognosic of renal failure following cardiac operations," The journal of thracic and Cardiirgy, 71(3), 1976, pp. 323-333.
[13] D. G. e. a. Hilberman M, "Sequential pathophysiological changes characterizing the progession from renal dysfuncition to acute renal failure following cardiac operation," The journal of thracic and Cardiirgy 79, 1980, pp. 838-844.