Successful valve-in-valve transcatheter aortic valve implantation using a hydra transcatheter aortic valve in a patient with severe degeneration of a surgical bioprosthesis: a case report

Thao Nguyen Phan1, , The Huy Nguyen, Le Anh Do, Cong Huu Nguyen
1 E Hospital

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Abstract

Bioprosthetic aortic valve degeneration is increasingly encountered and poses significant management challenges, particularly in elderly patients at high surgical risk [1]. Valve-in-valve transcatheter aortic valve implantation (ViV-TAVI) has emerged as an effective alternative to redo surgery in this complex population [1–3]. At the Cardiovascular centre, E Hospital, we report a case of 71-year-old man presenting with severe stenosis of a 21mm surgical bioprosthesis implanted 11 years earlier. Given the prohibitive risk of redo surgery [3], the Heart Team performed ViV-TAVI using a Hydra THV 22mm self-expanding transcatheter heart valve. The procedure was uneventful. At 15 days follow-up, transthoracic echocardiography demonstrated excellent hemodynamics performance with a peak transvalvular gradient of 9 mmHg and a mean gradient of 4 mmHg and the patient had returned to New York Heart Association (NYHA) functional class I.


This case highlights the feasibility and favorable early outcomes of Hydra THV in ViV-TAVI for small surgical bioprostheses, a subgroup frequently associated with high residual gradients and patient–prosthesis mismatch [5–7].


This report aims to describe a Valve-in-Valve TAVI procedure in a small bioprosthetic valve, emphasize the role of multimodality imaging, evaluate post-procedural hemodynamic outcomes, and discuss potential complications and preventive strategies, with particular focus on coronary obstruction and patient–prosthesis mismatch.

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References

1. Dvir D, Webb J. Valve-in-Valve TAVI: current status and future perspectives. EuroIntervention.
2. GENESIS Trial Investigators. Clinical performance of the Hydra THV. Catheter Cardiovasc Interv.
3. Webb JG, Mack M. Bioprosthetic valve failure and TAVI solutions. N Engl J Med.
4. Dvir D et al. Surgical vs transcatheter treatment of failed bioprosthetic valves. J Am Coll Cardiol.
5. Landes U, Webb JG, De Backer O, et al. Repeat transcatheter aortic valve replacement. J Am Coll Cardiol.
6. Pibarot P, Ternacle J, Jaber W. Hemodynamic performance of transcatheter valves in small annuli. J Am Coll Cardiol.
7. Dvir D, Barbanti M, Tan J, et al. Results from the VIVID registry. J Am Coll Cardiol.
8. De Jaegere P, Sathananthan J, Kamperidis V. Computer modeling to predict ViV performance. JACC Cardiovasc Interv.
9. Sathananthan J, Sellers S, Barlow A. Coronary obstruction in TAVR and ViV-TAVR. EuroIntervention.