Nhận xét một số đặc điểm lâm sàng, hình ảnh chụp cắt lớp vi tính và tổn thương mô bệnh học Sarcoma nhày nguyên phát ở phổi. Nhân một trường hợp
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Abstract
Reported here is an extremely rare case of primary pulmonary myxoid sarcoma (PPMS). A 30-year-old man presented with a 4,5cm-sized pulmonary tumor
surrounded by capsule-like fibrosis. This tumor focally showed endobronchial features, and consisted of reticular cords of oval, short spindle, or polygonal cells with swollen vesicular nuclei accompanied by an abundant myxoid stroma, closely resembling extraskeletal myxoid chondrosarcoma. Tumor cells were diffusely positive for vimentin and focally positive for epithelial membrane antigen, but were negative for CK7, TTF-1, MUC1, CK20, CDX-2, MUC2.
Article Details
Keywords
Key word: primary pulmonary myxoid sarcoma
References
2. Goetz SP, Robinson RA, Landas SK (1992) Extraskeletal myxoid chondrosarcoma of the pleura. Report of a case clinically simulating mesothelioma. Am J Clin Pathol 97(4):498–502.
3. Matsukuma S, Hisaoka M, Obara K, Kono T, Takeo H, Sato K, Hata Y (2012) Primary pulmonary myxoid sarcoma with EWSR1-CREB1 fusion, resembling extraskeletal myxoid chondrosarcoma: case report with a review of literature. Pathol Int 62(12):817–822. doi:10.1111/pin.12014.
4. Nicholson AG, Baandrup U, Florio R, Sheppard MN, Fisher C (1999) “Malignant myxoid endobronchial tumour: a report of two cases with a unique histological pattern”. Histopathology 35(4):31
5. Yoon Kyung Jeon, Kyung Chul Moon, SungHye Park, Doo Hyun Chung (2014) “Primary pulmonary myxoid sarcomas with EWSR1-CREB1 translocation might originate from primitive peribronchial mesenchymal cells undergoing (myo)fibroblastic differentiation” Virchows Arch (2014) 465:453–461.