Barlow severe mitral regurgitation: respect vs resect approaches in minimally invasive valve repair

Cong Hieu Luong, Hoang Dinh Nguyen1,
1 University Medical Center HCMC

Main Article Content

Abstract

Introduction: Barlow’s disease represents the most severe form of degenerative mitral valve disease, with mitral regurgitation as its most common manifestation. According to current treatment guidelines, severe symptomatic mitral regurgitation warrants surgery, with mitral valve repair being preferred over replacement due to its favorable impact on patient prognosis. Mitral valve repair techniques are broadly classified into two main approaches: resect and respect. In Barlow’s disease, characterized by significant excess valve tissue, the choice between these two approaches in minimally invasive surgery remains controversial. This study aimed to compare the early outcomes of resect and respect approaches in minimally invasive mitral valve repair for patients with Barlow’s disease.


Methods: This retrospective cohort study included all patients with severe mitral regurgitation and Barlow-type mitral valve who underwent minimally invasive mitral valve repair from 2020 to 2024 at the University Medical Center in Ho Chi Minh City, with complete data available for analysis.


Results: A total of 61 patients met the inclusion criteria. Successful valve repair was achieved in 57 patients (93.4%), while 4 cases required valve replacement due to complex valve pathology. Among the 57 patients who underwent repair, 26 patients (45.6%) received mitral valve repair using the respect approach, while 31 patients (54.4%) were treated with the resect approach. The mean cardiopulmonary bypass time and aortic cross-clamp time were 146.1 ± 23.8 minutes and 84.6 ± 15.9 minutes, respectively. During the 30-day postoperative follow-up, no mortality or SAM (systolic anterior motion) complications were observed, with one case of moderate mitral regurgitation post-surgery. Additionally, no reoperations were required during the follow-up period.


Conclusion: Minimally invasive mitral valve repair for Barlow’s disease shows favorable outcomes within the first 30 postoperative days. The resect and respect approaches yield comparable results.

Article Details

References

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