Initial results of endovascular drug-eluting stent placement for the treatment of chronic lower extremity arterial disease at Thong Nhat Hospital

Duy Tan Nguyen1,2, Tan Nguyen Khoi Nguyen, Thao Cuong Lam3,4,
1 Thong Nhat Hospital
2 Vietnam National University Ho Chi Minh City
3 University Medical Center Ho Chi Minh City
4 University of Medicine and Pharmacy at Ho Chi Minh City

Main Article Content

Abstract

Introduction: Chronic lower extremity arterial disease is increasingly common, particularly among elderly patients with multiple comorbidities. Drug-eluting stents have emerged as an effective endovascular option, offering improved patency and reduced restenosis. This study is to evaluate the initial outcomes of drug-eluting stent placement for chronic lower extremity arterial disease at Thong Nhat Hospital.


Patients and Methods: A retrospective case-series study was conducted on 35 patients with chronic lower extremity arterial disease who underwent endovascular drug-eluting stent placement between 1/2022 and 12/2024. Outcome measures included changes in Rutherford classification, ankle–brachial index (ABI), wound healing rate, vascular patency, and mortality. Clinical and imaging follow-up assessments were performed at 6, 12, and 24 months after the intervention.


Results: Significant improvement in clinical symptoms and ABI values was observed at follow-up (p < 0.001). Wound healing rates were 84.6% at 6 months and 100% at 24 months. Primary patency at 24 months was 88.6%.


Conclusions: Drug-eluting stent placement demonstrates favorable mid-term efficacy in improving limb perfusion and wound healing with an acceptable safety profile in patients with chronic lower extremity arterial disease.

Article Details

References

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