SỬ DỤNG DUNG DỊCH LIỆT TIM MÁU ẤM ĐỂ BẢO VỆ CƠ TIM TRONG PHẪU THUẬT TIM NGƯỜI LỚN

Abstract

We retrospectively analyzed, over 14 years (2004-2018), early results of cardiac surgical patients (n=6720) using warm blood cardioplegia for myocardial protection. We access the myocardial cell injury base on research variables collected before surgery, 2h, 8h and 24h postoperatively of cardiac troponin T level, spontaneous defibrillation after removing aortic clamp, use of intra-aortic balloon counter pulsation (IABP), and use of inotropic support, and evaluated cardiac function such as cardiac output measurement, left ventricular ejection fraction as well as the clinical outcome such as ventilation time and ICU stay in these patients. Results: Preoperative demographic and clinical variables with high risk factors were severe heart failure at NYHA.III-IV (81,3%), severe pulmonary artery hypertension (27,7%) and patients undergoing complicated surgery (39,3%) such as multi-valvular surgery or combined valvular and coronary surgery… and long duration in aortic clamp (40,5%) or in cardiopulmonary bypass (40,2%). However, postoperatively, there was a significantly goof progress in cardiac function such as left ventricular ejection fraction (p<0,05), cardiac output (p<0,05) and in clinical outcome such as reduced ventilation time (22,56±30,04 hours) as well as ICU stay (51,16±35,13 hours).