Đánh giá hiệu quả kinh tế của Sevoflurane so với Propofol dùng để duy trì mê trong giai đoạn tuần hoàn ngoài cơ thể trên bệnh nhân phẫu thuật tim hở

Abstract

Objectives: To evaluate the cost-effectiveness between Sevoflurane and Propofol for anesthesia during cardiopulmonary bypass. Methods: A prospective cross-sectional study was implemented on 60 patients from August 2019 to January 2020. Mean of age was 56.17±10.99 (18-75). Male: 45%, female: 55%. Patients were selected and divided into 2 groups (S group and P group) using simple random sampling. After being anesthetized, the patients in S group received Sevoflurane through oxygen mixer on cardiopulmonary bypass while P group received intravenous Propofol. During maintenance of anesthesia, controlled depth of anesthesia (BIS 40-60) was achieved in both groups. Data related to cost of drugs, labor, medical consumables and equipment were carefully and honestly recorded in order to calculate the specific cost for each group. Results: Cost of drugs: S group 80.293 ± 37.203 VND; P group 158.891 ± 69.414 VND. Cost of supplies and resources: S group 579.83 ± 829.658 VND; P group 26.368,87 ± 7.764,484 VND. Cost of labor: S group 579.83 ± 829.658 VND; P group 26.368,87 ± 7.764,484 VND. Total cost: S group 81.622,85 ± 37.537,78 VND; P group 189.327,16 ± 76.456,76 VND. Conclusion: Sevoflurane is more cost-effective than Propofol for anesthesia maintenance during cardiopulmonary bypass on open-heart surgery patients (p < 0.001). Anesthesia maintenance by Sevoflurane during cardiopulmonary bypass is feasible, safety and economical